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Suppose Balto didn't deliver the medicine? The desease might have spread, and with transport, it might have spread across the world! Even if antidotes are in other places, they would surly run out. So, maybe Balto saved the world.

Hmmm...it would take a long time to affect the world...

But even though other mushers joined serum run, most of them failed. Eventually, a team would probably make it, and your right about it being a desolate place.

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The only way I see it would "Effect the entire world" was if infected people travled and went around the world spreading the sickness. But I doubt they would have already died before they could.
Correction: Balto and many other brave dogs and mushers atempted and helped save the children of Nome.
But still, Balto helped save some lives.

Nome only ran out of the antidote (forget the name) so that doesn't mean other places ran out too. If it spread towns/cities/countries (if it got that far) would just treat themselves

It could happen that way today; scientists have calculated that with the way people get around, a disease (particularly one engineered) could be in every country on the planet in a mere few weeks of the first infection.

But back then they traveled less, so probably not.

Haha, that's a funny plot idea, but NO that wouldn't happen. Besides Nome, at the time, was a rural area. It couldn't have traveled the world and if it did we would have found a way to fight the virus.

The influenza epidemic in Nome, in 1918, was brought into the region by immigrants and migrants coming in by ship from the lower 48. Small pox also frequently spread that way. And the flu epidemic hit Nome very hard. Those steam ships were often crowded to the gunwales and then some...and several times in Nome's first year or so, steam ships bringing hopefuls who wanted to strike it rich in the gold fields often were quaranteened before reaching the Nome area. Sometimes, and this is documented, they actually put people ashore on small islands to be quaranteened until medical help could be rendered...effectively stranding them for quite a lengthy, and unpleasant, stay.

Those others from the Lower 48, (U.S.) were coming up from there because of the Gold Rush that only lasted several years. I didn't know they sent a disease too... It's kind of like the Spanish bringing Smallpox to the Aztecs in 1519!